|
Fplus
Nuovo Arrivato
100 Messaggi |
 Inserito il - 19 luglio 2011 : 10:20:45
|
qualcuno ha studiato questa malattia? io ho una rewiev dove non capisco questa foto che dice....
Immagine:
14,08 KB
la spiegazione della fig è:
Figure 1. Long-Range Restriction Map of the
HD Candidate Region
A partial long-range restriction map of 4~16.3
is shown (adapted from Lin et al. 119911). The
HD candidate region determined by recombination
events is depicted by hatched bars between
D4SiO and D4S98. The portion of the
HD candidate region implicated as the site of
the defect by linkage disequilibrium haplotype
analysis (MacDonald et al., 1992) is shown as
a closed bar. Below the schematic map, the
region from D4S780 to D4S182 is expanded to
show the cosmid contig (averaging 40 kb per
cosmid). The genomic coverage and, where
known, the transcriptional orientation (arrows,
__ LlalFl
L11386 L83D3 ~ LlSlSlO LIIOFS
5’ to 3’) of the IT1 5, IT1 1, IT1 OC3, and ADDA
- __
- SJ58
genes is also shown. Locus names above the
map denote selected polymorphic markers that
have been used in HD families. The positions
of 045727 and D4S95, which form the core of
4 1 n - haplotype in the region of maximum disequilib-
IT15 IT11 ITlOC3 ADDA rium, are also shown in the cosmid contig. Restriction
sites are given for Notl (N), Mlul (M),
and Nrul (R). Sites displaying complete digestion are shown in boldface, while sites subject to frequent incomplete digestion are shown as lighter
symbols. Brackets around the N symbols indicate the presence of additional clustered Notl sites.
qualkuno può aiutarmi?
|
|
corea di huntington
